Microorganisms and Viruses
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- Photo: Jürgen Kneifel, Hessen schafft Wissen
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- Photo: Jürgen Kneifel, Hessen schafft Wissen
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- Photo: Jürgen Kneifel, Hessen schafft Wissen
- Short Description
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This Campus Research Focus pools the molecular, ecological and medical expertise in microbiology, virology and parasitology of the universities of Giessen and Marburg and the THM University of Applied Sciences, with the cooperation partners Max Planck Institute for Terrestrial Microbiology in Marburg, Paul Ehrlich Institute in Langen and the University Hospital of Giessen and Marburg.
In microbiology, the interdisciplinary field of research addresses the entire spectrum of microorganisms with their ecology, pathogenesis, genetics and evolution as well as the pioneering topics of synthetic microbiology and recycling processes.
In virology the focus is on the deciphering of the molecular mechanisms of common viral diseases such as influenza on the one hand and emerging diseases caused by Ebola- or MERS coronavirus on the other.
Parasitology research concentrates on malaria and schistosomiasis, as well as infection models and the development of active agents and vaccines.
All areas involved in this Campus Research Focus aim to obtain a basic mechanistic understanding of microbes and viruses from the molecular and cellular level via microbiotic communities all the way through to preclinical models. In this context, the researchers are particularly interested in identifying overarching strategies that microbes and viruses use, and seeing how they interact – with each other and with the host. The focus of the translational research here is on the prevention and treatment of infectious diseases, the utilisation of microorganisms, the improvement of technologies in the pharmaceutics industry, the agricultural sciences and the chemicals industry.
These approaches of basic and translational research lead to close cooperation with the campus research areas "Infection and Inflammation", "Insect Biotechnology and Bioresources", "Digital Medicine and E-Health" and "Lung and Heart", as well as the Research Division Bioresources of the Fraunhofer Institute for Molecular Biology and Applied Ecology (IME) in Giessen.
- Successful Joint Research
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Microcosm Earth Center
Funding Period: 2023 to 2030 -
DFG Research Training Group GRK-2937: "Nucleotide Metabolism in Microbes (MiNu)"
Funding Period: 2023 to 2032 -
LOEWE-Focus: Tree-M - Mechanisms of resilience and environmental impact of the leaf microbiome of trees
Funding Period: 2023 to 2026 -
LOEWE-Focus: CoroPan - Human and zoonotic coronaviruses: conserved targets for new therapeutic options in future pandemics
Funding Period: 2023 to 2026 -
LOEWE-Focus: Diffusable Signals - Impact of Diffusable Signals At Human Cell-Microbe Interfaces
Funding Period: 2021 to 2025 -
DFG Collaborative Research Center SFB 1021: RNA Viruses: Metabolism of Viral RNA, Host Cell Immune Response and Viral Pathogenesis (joint project with the campus foci Hospital Hygiene and Microbiology and Virology)
Funding Period: 2013 to 2025 - DFG Collaborative Research Centre CRC 84: Innate Immunity of the Lung: Mechanisms of Pathogen Attack and Host Defence in Pneumonia
Funding Period: 2010 to 2023
- DFG Collaborative Research Centre CRC/Transregio 81: Chromatin Changes in Differentiation and Malignancies
Funding period: 2010 to 2022
- DFG Collaborative Research Centre CRC/Transregio 174: Spatiotemporal dynamics of bacterial cells
Funding period: 2017 to 2021
- DFG Collaborative Research Centre CRC 987: Microbial Diversity in Environmental Signal Response
Funding period: 2012 to 2024
- DFG Collaborative Research Centre Transregio CRC/Transregio 174: Spatiotemporal Dynamics of Bacterial Cells
Funding period: 2017 to 2020
- DFG Collaborative Research Centre CRC 1021: RNA Viruses – RNA Metabolism, Host Response and Pathogenesis
Funding period: 2013 to 2024
- DFG Collaborative Research Centre CRC 593: Mechanisms of Cellular Compartmentation and the Relevance for Disease
Funding period: 2003 to 2014
- DFG Collaborative Research Centre CRC 535: Invasion Mechanism and Replication Strategies of Infectious Agents
Funding period: 1997 to 2008
- DFG Collaborative Research Centre CRC 395: Interaction, Adaptation and Catalytic Capability of Soil Microorganisms
Funding period: 1996 to 2007
- Participation in DFG Priority Programme SPP 1935: Deciphering the mRNP code: RNA-bound determinants of post-transcriptional gene regulation
Funding Period: since 2016
- DFG Priority Programme SPP 1710: Dynamics of Thiol-Based Redox Switches in Cellular Physiology
Funding period: 2014 to 2022
- Participation in DFG Priority Programme SPP 1596: Ecology and Species Barriers in Emerging Viral Diseases; subproject "Antiviral Factors of Type 1-Interferon Systems of Small Mammals"
Funding Period: 2013 to 2020
- DFG Research Training Group RTG 2355: Regulatory networks in the mRNA life cycle: from coding to noncoding RNAs
Funding Period: 2018 to 2028
- DFG Research Training Group RTG 2213: Membrane Plasticity in Tissue Development and Remodeling
Funding period: 2016 to 2021
- DFG International Research Training Group IRTG 767: Transcriptional Control in Developmental Processes
Funding period: 2002 to 2010
- DFG Clinical Research Unit KFO 309: Virus-induced Lung Injury: Pathobiology and Novel Therapeutic Strategies
Funding period: 2016 to 2022
- LOEWE Centre: Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases (DRUID)
Funding period: 2018 to 2023 - LOEWE Research Cluster: MOSLA – Molecular Long-Term Data Storage
Funding period: 2019 to 2023
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- Research Infrastructure
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- High Security BSL-4-Laboratory at Philipps-Universität Marburg – the only laboratory of its kind at a university in Germany
- “BiGi - The Bielefeld-Giessen Resource Center for Microbial Bioinformatics” – In cooperation with the campus research focus “Biomedical Informatics and E-health”
- DFG core facility: Marburg Core Facility for Interactions, Dynamics and Macromolecular Assembly Structure
German Research Foundation. Coordinator: Dr. G. Bange/UMR, 2016; UMR
- Centre for Synthetic Microbiology (SYNMIKRO) – joint research institution by the Philipps-Universität Marburg and the Max Planck Institute for Terrestrial Microbiology (from 2011 to 2018 funded through LOEWE)
- Research Environment
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- German Centre for Infection Research (DZIF); the Justus Liebig University, Philipps-Universitaet Marburg, Technische Hochschule Mittelhessen University of Applied Sciences and the Paul-Ehrlich-Institut Langen form the DZIF-site Gießen-Marburg-Langen; speaker Trinad Chakraborty (JLU), deputy speaker Stephan Becker (UMR)
- Paul-Ehrlich Institute, Langen – Federal Institute for Vaccines and Biomedicines
- Max Planck Institute for Heart and Lung Research, Bad Nauheim
- Participating Researchers
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At Justus Liebig University Gießen
- Prof. Dr. Katja Becker
Biochemistry and Molecular Biology, Faculty of Agricultural Sciences,Ecotrophology and Environmental Management, JLU - Dr. Bork Berghoff
Microbiology and Molecular Biology, Faculty of Biology and Chemistry, JLU - Prof. Dr. Albrecht Bindereif
Biochemistry, Faculty of Biology and Chemistry, JLU - Prof. Dr. Trinad Chakraborty
Medical Microbiology, Medical Faculty, JLU - Prof. Dr. Eugen Domann
Medical Microbiology, Medical Faculty, JLU - PD Dr. Elena Evguenieva-Hackenberg
Microbiology and Molecular Biology, Faculty of Biology and Chemistry, JLU - Prof. Dr. Linda Falgenhauer
Institute for Medical Microbiology, JLU - Jane Falgenhauer
Institute for Medical Microbiology, JLU - Dr. Moritz Fritzenwanker
Institute for Medical Microbiology, JLU - Prof. Dr. Stefan Gäth
Waste Management and Environmental Research, Faculty of Agricultural Sciences,Ecotrophology and Environmental Management, JLU - Prof. Dr. Dieter Glebe
Medical Virology, Medical Faculty, JLU - Prof. Dr. Alexander Goesmann
Bioinformatics and Systems Biology, Faculty of Biology and Chemistry and Zentrum für Synthetische Mikrobiologie SYNMIKRO, JLU - Prof. Dr. Christoph Grevelding
Faculty of Veterinary Medicine, Institute for Parasitology, JLU - Prof. Dr. Susanne Herold
Acute Lung Injury, Medical Faculty, JLU - Dr. Sybille Herzog
Virology, Faculty of Veterinary Medicine, JLU -
Prof. Dr. Dr. Peter Kämpfer
Microbiology of Recycling Processes, Faculty of Agricultural Sciences,Ecotrophology and Environmental Management, JLU - Prof. Dr. Gabriele Klug
Microbiology and Molecular Biology, Faculty of Biology and Chemistry, JLU - Prof. Dr. Karl-Heinz Kogel
Phytopathology, Faculty of Agricultural Sciences,Ecotrophology and Environmental Management, JLU - Dr. Matthias König
Virology, Faculty of Veterinary Medicine, JLU - Prof. Dr. Michael Kracht
Pharmacology, Medical Faculty, JLU - Prof. Dr. Stephan Pletschka
Medical Virology, Medical Faculty, JLU - Dr. Martin Rühl
Food Chemistry and Food Biotechnology, Faculty of Biology and Chemistry, JLU - Prof. Dr. Christos Samakovlis
Molecular Pneumology, Medical Faculty, JLU - Prof. Dr. Till Schäberle
Natural producst research with a Focus on Insect Biotechnology, Faculty of Agricultural Sciences,Ecotrophology and Environmental Management, JLU - Prof. Dr. Sylvia Schnell
General and Soil Microbiology, Faculty of Agricultural Sciences,Ecotrophology and Environmental Management, JLU - Dr. Christian Schüttler
Medical Virology, Medical Faculty, JLU - Prof. Dr. Werner Seeger
Internal Medicine, Medical Faculty, JLU - Prof. Dr. Bernhard Spengler
Anorganic and Analytic Chemistry, Faculty of Biology and Chemistry, JLU - Prof. Dr. Katja Sträßer
Biochemistry, Faculty of Biology and Chemistry, JLU - Prof. Dr. med. vet. Anja Taubert
Faculty of Veterinary Medicine, Institute for Parasitology, JLU - Prof. Dr. Gergely Tekes
Virology, Faculty of Veterinary Medicine, JLU - Prof. Dr. Kai Thormann
Microbiology and Molecular Biology, Faculty of Biology and Chemistry, JLU - Prof. Dr. Andreas Vilcinskas
Applied Entomology, Faculty of Agricultural Sciences, Ecotrophology and Environmental Management, JLU - Prof. Dr. Friedemann Weber
Virology, Faculty of Veterinary Medicine, JLU - Prof. Dr. John Ziebuhr
Medical Virology, Medical Faculty, JLU - Prof. Dr. Holger Zorn
Food Chemistry and Food Biotechnology, Faculty of Biology and Chemistry, JLU
At Philipps-Universität Marburg
- Prof. Dr. Gert Bange
Molecular Plasticity of Microbial Adaptation, Zentrum für Synthetische Mikrobiologie SYNMIKRO and Faculty of Chemistry, UMR - Prof. Dr. Stefan Bauer
Immunobiology, Medical Faculty, UMR - Dr. Anke Becker
Comparative Genomics, Zentrum für Synthetische Mikrobiologie SYNMIKRO and Faculty of Biology, UMR - Prof. Dr. Stephan Becker
Virology, Medical Faculty, UMR - Dr. Patricia Bedrunka
Center for Synthetic Microbiology (SYNMIKRO) - Prof. Dr. Michael Bölker
Genetics, Faculty of Biology and Zentrum für Synthetische Mikrobiologie SYNMIKRO, UMR - Prof. Dr. Erhard Bremer
Moloecular Microbiology, Faculty of Biology and Zentrum für Synthetische Mikrobiologie SYNMIKRO, UMR - Prof. Dr. Lars-Oliver Essen
Structural Biochemistry, Faculty of Chemistry and Zentrum für Synthetische Mikrobiologie SYNMIKRO, UMR - Prof. Dr. Eva Frieberthäuser
Virology, Medical Faculty, UMR - Dr. Georg Fritz
Quantitative and Computational Microbiology, Zentrum für Synthetische Mikrobiologie SYNMIKRO and Faculty of Physics, UMR - Prof. Dr. Peter Graumann
Molecular and cellular biochemistry of microorganisms, Zentrum für Synthetische Mikrobiologie SYNMIKRO and Faculty of Chemistry, UMR - Prof. Dr. Roland Hartmann
Pharmaceutical Chemistry, Faculty of Pharamceutics, UMR - Prof. Dr. Dominik Heider
Bioinformatics, Faculty of Mathematics and informatics and Zentrum für Synthetische Mikrobiologie SYNMIKRO, UMR - Prof. Dr. Johann Heider
Microbial Biochemistry, Faculty of Biology and Zentrum für Synthetische Mikrobiologie SYNMIKRO, UMR - Prof. Dr. Magdalena Huber
Medical Microbiology, Medical Faculty, UMR - Prof. Dr. Gerhard Klebe
Pharmaceutical Chemistry, Faculty of Pharamceutics and Zentrum für Synthetische Mikrobiologie SYNMIKRO, UMR - Dr. Peter Kolb
Pharmaceutical Chemistry, Faculty of Pharamceutics and Zentrum für Synthetische Mikrobiologie SYNMIKRO, UMR - Dr. Marcus Lechner
Department of Pharmacy - Prof. Dr. Peter Lenz
Complex Systems, Faculty of Physics and Zentrum für Synthetische Mikrobiologie SYNMIKRO, UMR - Prof. Dr. Shu-Ming Li
Pharmaceutical Biology and Biotechnology, Fachbereich Pharmazie und Zentrum für Synthetische Mikrobiologie SYNMIKRO, UMR - Prof. Dr. Roland Lill
Cytobiology, Medical Faculty and Zentrum für Synthetische Mikrobiologie SYNMIKRO, UMR - Prof. Dr. Michael Lohoff
Medical Microbiology, Medical Faculty, UMR - Prof. Dr. Uwe Maier
Cell Biology, Faculty of Biology and Zentrum für Synthetische Mikrobiologie SYNMIKRO, UMR - Prof. Dr. Andrea Maisner
Virology, Medical Faculty, UMR - Dr. Mikhail Matrosovich
Virology, Medical Faculty, UMR - Prof. Dr. Eric Meggers
Chemical Biology, Faculty of Chemistry, UMR - Dr. Hans-Ulrich Mösch
Molecular Genetics, Faculty of Biology and LOEWE-Zentrum für Synthetische Mikrobiologie SYNMIKRO, UMR - Prof. Dr. Lennart Randau
Department of Biology - Dr. Stefan Rensing
Cell Biology, Faculty of Biology and Zentrum für Synthetische Mikrobiologie SYNMIKRO, UMR - Prof. Dr. Harald Renz
Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Medical Faculty, UMR - Prof. Dr. Bernd Schmeck
Lung research, Medical Faculty, UMR - Prof. Dr. Markus Schnare
Immunlogie, Medical Faculty, UMR - Dr. Jan Michael Schuller
Center for Synthetic Microbiology (SYNMIKRO) - Jun.-Prof. Dr. Leon Schulte
Lung research, Medical Faculty, UMR - PD Dr. Frank Sommer
Medizinische Mikrobiologie, Fachbereich Medizin, UMR - Prof. Dr. Ulrich Steinhoff
Medical Microbiology, Medical Faculty, UMR - Dr. Thomas Strecker
Virologie, Medical Faculty, UMR - Prof. Dr. Martin Thanbichler
Bacterial Cell Biology, Faculty of Biology and Zentrum für Synthetische Mikrobiologie SYNMIKRO, UMR - Prof. Dr. Olalla Vazquez
Department of Chemistry - PD Dr. Hans Günther Wahl
Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Medical Faculty, UMR - Prof. Dr. Torsten Waldminghaus
Chromosome Biology, Zentrum für Synthetische Mikrobiologie SYNMIKRO and Faculty of Biology, UMR
At Technische Hochschule Mittelhessen University of Applied Sciences
- Prof. Dr. Peter Czermak
Bioprocess Engineering and Pharmaceutical Technology, Faculty of Life Science Engineering, THM - Prof. Dr. Martin Fiebich
Medical Physics and Radiation Protection, Faculty of Life Science Engineering, THM
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Prof. Dr. Frank Runkel
Bioprocess Engineering and Pharmaceutical Technology, Faculty of Life Science Engineering, THM - Prof. Dr. Klemens Zink
Medical Physics and Radiation Protection, Faculty of Life Science Engineering, THM
- Prof. Dr. Katja Becker
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